منابع مشابه
Antibodies against oxidized LDL in infants.
To the Editor: We conducted two studies of serum antibodies against oxidized LDL (IgoxLDL) in mothers and their infants during the past 2 years. We used an ELISA (oLAb; Eli-Tec Labor-reagenzien GmbH) based on the use of Cu 2ϩ-oxidized LDL particles bound to the surface of microtiter plate wells and an anti-human IgG-peroxidase conjugate. In the first study of mothers and their infants at birth ...
متن کاملAntibodies against oxidized LDL--theory and clinical use.
Modification of low density lipoprotein (LDL) particles due to oxidation, glycation and binding of advanced glycation end-products (AGEs) or malondialdehyde (MDA, a final product of lipid peroxidation) is considered most important in the process of atherogenesis. Oxidatively modified LDL are distinguished by another receptor type, which was discovered on the surface of macrophages and was calle...
متن کاملIs the Ratio of Antibodies Against Oxidized LDL to Oxidized LDL an Indicator of Cardiovascular Risk in Psoriasis?
OBJECTIVES Psoriasis is a chronic inflammatory skin disease. Chronic inflammation results in increased oxidative stress and oxidizes lipoproteins, increasing their atherogenicity. This study sought to estimate the levels of oxidized low-density lipoprotein (ox-LDL) and antibodies against oxidized LDL (anti-ox-LDL) and compute the ratio of anti-ox-LDL/ox-LDL as a single composite parameter to as...
متن کاملThe preparation of copper-oxidized LDL for the measurement of oxidized LDL antibodies by EIA.
In the present study we try to define the optimal conditions for preparation of copper-oxidized low-density lipoprotein (oxLDL) to be used for the assay of oxLDL antibodies by enzyme immunoassay (EIA). Oxidation of LDL was monitored by measuring the formation of conjugated dienes at 234 nm and the generation of fluorescent products with emission at 430 nm when excitation is performed at 360 nm....
متن کاملAntibodies against oxidized LDL and carotid artery intima-media thickness in a healthy population.
Oxidation of LDLs plays an important role in atherosclerosis, and immune response to oxidized LDL (oxLDL) may modulate atherogenesis. Although immunization with oxLDL is shown to suppress atherogenesis in animal models, the role of the immune response to oxLDL is not well established in humans. We investigated the relationship between the titer of anti-oxLDL antibody (oxLDL Ab) and arterial wal...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2001
ISSN: 0009-9147,1530-8561
DOI: 10.1093/clinchem/47.6.1137